Earth Watch Report - Biological Hazards
A dry fracture of a Vero cell exposing the contents of a vacuole where Coxiella burnetii are busy growing. National Institute of Allergy and Infectious Diseases (NIAID)
Author : National Institutes of Health (NIH)
Wikipedia.org
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Biological Hazard | Spain | Basque Country, Bilbao |
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RSOE EDIS
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Combination of two x-rays found on the two websites http://www.fda.gov/cdrh/ct/what.html FDA website with normal chest x-ray http://www.cdc.gov/ncidod/eid/vol6no1/scrimgeourG2.htm CDC website documenting Q fever pneumonia All editing performed by me and released into public domain
Wikipedia.org
Signs and symptoms
Incubation period is usually two to three weeks.[8] The most common manifestation is mild flu-like symptoms with abrupt onset of fever, malaise, profuse perspiration, severe headache, myalgia (muscle pain), joint pain, loss of appetite, upper respiratory problems, dry cough, pleuritic pain, chills, confusion and gastrointestinal symptoms, such as nausea, vomiting and diarrhea. The fever lasts approximately seven to 14 days.[citation needed]Approximately half of infected individuals exhibit no symptoms.[8]
During its course, the disease can progress to an atypical pneumonia, which can result in a life-threatening acute respiratory distress syndrome (ARDS), whereby such symptoms usually occur during the first four to five days of infection.[citation needed]
Less often, Q fever causes (granulomatous) hepatitis, which may be asymptomatic or becomes symptomatic with malaise, fever, liver enlargement (hepatomegaly) and pain in the right upper quadrant of the abdomen. Whereas transaminase values are often elevated, jaundice is uncommon. Retinal vasculitis is a rare manifestation of Q fever.[9]
The chronic form of Q fever is virtually identical to inflammation of the inner lining of the heart (endocarditis),[10] which can occur months or decades following the infection. It is usually fatal if untreated. However, with appropriate treatment, the mortality falls to around 10%.
Clinical signs in animals
Cattle, goats and sheep are most commonly infected, and can serve as a reservoir for the bacteria. Q fever is a well recognized cause of abortions in ruminants and in pets. C. burnetii infection in dairy cattle has been well documented and its association with reproductive problems in these animals has been reported in Canada, USA, Cyprus, France, Hungary, Japan, Switzerland and West Germany.[11] For instance, in a study published in 2008,[12]a significant association has been shown between the herds’ seropositivity and typical clinical signs of Q Fever observed such as abortion, stillbirth, weak calves and repeat breeding. Moreover, experimental inoculation of C. burnetii in cattle induced not only respiratory disorders and cardiac failures (myocarditis) but also frequent abortions and irregular repeat breedings.[13]Read More Here
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