Earth Watch Report - Biological Hazards
Biological Hazard | USA | State of Virginia, [The area was not defined.] |
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National Hog Farmer
Porcine Epidemic Diarrhea (PED) Virus: FAQ and Survival Tips
Iowa
State University swine veterinarians provide answers to some of the
most-asked questions about Porcine Epidemic Diarrhea (PED) virus.
By now, swine producers should be well aware of the emergence of porcine epidemic diarrhea (PED) virus in the United States. Do not underestimate the likelihood of transmission to your herd; this is a sneaky virus.
Some answers to common questions asked at the diagnostic laboratory follow, as well as tidbits on how to understand disease impact and decreases losses of suckling pigs.
What is PED Virus?
Porcine epidemic diarrhea (PED) virus is a disease occurring only in pigs, caused by a coronavirus that does exactly what the disease name implies: produces acute and severe outbreaks of diarrhea that rapidly transmits among all ages of pigs (epidemic).
Where did PED virus come from? Sequence data from U.S. strains thus far suggests all to be very similar to a strain deposited in GenBank from China in 2012. PED virus is present in many countries in Asia and has been present in Europe since the 1970s.
How common is PED Virus in the United States?
Data provided by veterinary diagnostic laboratories to the National Animal Health Laboratory Network (NAHLN) suggests that there are 40-50 new cases of PED virus diagnosed each week, with the disease now reported in 14 states. The epidemic form of the disease is easy to recognize clinically so samples may not always be submitted to a laboratory, hence currently reported data likely underestimates true prevalence. An accurate estimate of U.S. prevalence is difficult to achieve and will eventually need to rely on serologic surveys, particularly if the disease becomes endemic.
How did PED virus get into the United States?
There is no confirmation of particular source or location of entry of the virus. Speculation abounds, but it is unlikely that we will ever know how PED virus entered the United States with certainty. However, this does provide the opportunity to scrutinize the possibilities to prevent future events.
How is PED virus spread?
Huge numbers of virus particles are shed in feces. One thimble-full of feces could contain enough virus to infect all the pigs in the United States. The PED virus is being detected in samples collected from pig collection points, slaughter facilities, transportation vehicles and innumerable fomites illustrating the vast potential for transmission. It is expected that survivability and transmission of virus will be enhanced in cold weather. Farm biosecurity efficacy is likely to be tested aggressively in the coming months.
How do I get an accurate diagnosis of PED virus?
If PED virus is suspected, consult your veterinarian. Sometimes, 10 ml of feces from acutely affected pigs tested by polymerase chain reaction (PCR) is sufficient to confirm the presence of virus. However, submission of tissues from acutely affected pig(s) for complete diagnostic testing (bacteria, viruses, parasites) will allow for diagnosis of PED virus as well as other diseases. The value of histopathology and immunohistochemistry (IHC) testing is illustrated in Figures 1-4 below. Sampling tips are found at http://vetmed.iastate.edu/vdpam/disease-topics/porcine-epidemic-diarrhea-ped-diagnostic-testing as well as the addendum below.
What is the impact of PED virus in weaned pigs?
Once pigs are weaned, the mortality rate from PED virus plummets. When not complicated by other diseases, pigs in nursery-finisher stages generally recover in about a week. The rumors of severe disease or high mortality in weaned pigs usually involve co-infections with salmonella or hemolytic E. coli or other risk factors associated with the environment or feeding practices.
Some answers to common questions asked at the diagnostic laboratory follow, as well as tidbits on how to understand disease impact and decreases losses of suckling pigs.
What is PED Virus?
Porcine epidemic diarrhea (PED) virus is a disease occurring only in pigs, caused by a coronavirus that does exactly what the disease name implies: produces acute and severe outbreaks of diarrhea that rapidly transmits among all ages of pigs (epidemic).
Where did PED virus come from? Sequence data from U.S. strains thus far suggests all to be very similar to a strain deposited in GenBank from China in 2012. PED virus is present in many countries in Asia and has been present in Europe since the 1970s.
How common is PED Virus in the United States?
Data provided by veterinary diagnostic laboratories to the National Animal Health Laboratory Network (NAHLN) suggests that there are 40-50 new cases of PED virus diagnosed each week, with the disease now reported in 14 states. The epidemic form of the disease is easy to recognize clinically so samples may not always be submitted to a laboratory, hence currently reported data likely underestimates true prevalence. An accurate estimate of U.S. prevalence is difficult to achieve and will eventually need to rely on serologic surveys, particularly if the disease becomes endemic.
How did PED virus get into the United States?
There is no confirmation of particular source or location of entry of the virus. Speculation abounds, but it is unlikely that we will ever know how PED virus entered the United States with certainty. However, this does provide the opportunity to scrutinize the possibilities to prevent future events.
How is PED virus spread?
Huge numbers of virus particles are shed in feces. One thimble-full of feces could contain enough virus to infect all the pigs in the United States. The PED virus is being detected in samples collected from pig collection points, slaughter facilities, transportation vehicles and innumerable fomites illustrating the vast potential for transmission. It is expected that survivability and transmission of virus will be enhanced in cold weather. Farm biosecurity efficacy is likely to be tested aggressively in the coming months.
How do I get an accurate diagnosis of PED virus?
If PED virus is suspected, consult your veterinarian. Sometimes, 10 ml of feces from acutely affected pigs tested by polymerase chain reaction (PCR) is sufficient to confirm the presence of virus. However, submission of tissues from acutely affected pig(s) for complete diagnostic testing (bacteria, viruses, parasites) will allow for diagnosis of PED virus as well as other diseases. The value of histopathology and immunohistochemistry (IHC) testing is illustrated in Figures 1-4 below. Sampling tips are found at http://vetmed.iastate.edu/vdpam/disease-topics/porcine-epidemic-diarrhea-ped-diagnostic-testing as well as the addendum below.
What is the impact of PED virus in weaned pigs?
Once pigs are weaned, the mortality rate from PED virus plummets. When not complicated by other diseases, pigs in nursery-finisher stages generally recover in about a week. The rumors of severe disease or high mortality in weaned pigs usually involve co-infections with salmonella or hemolytic E. coli or other risk factors associated with the environment or feeding practices.
Read More here
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National Hog Farmer
Virginia Confirms PEDV Outbreak, Focuses on Biosecurity
Richard
Wilkes, DVM, State Veterinarian with the Virginia Department of
Agriculture and Consumer Services (VDACS), recently announced that
Virginia has just received laboratory confirmation of its first case of
porcine epidemic diarrhea virus (PEDV) in the state. In light of this
case, which coincides with the beginning of the exhibit season for 4-H
members, FFA students and other livestock exhibitors, Wilkes says strict
biosecurity is the most effective, as well as the most practical way to
prevent the spread of PEDV and many other livestock and poultry
diseases.
Wilkes encourages every person involved in showing livestock to enhance their biosecurity efforts. He noted that the VDACS always urges livestock owners who show their animals, as well as those individuals who manage show and exhibition facilities to keep biosecurity uppermost in their minds.
However, Wilkes said that with swine it is even more important now that Virginia has experienced its first case of PEDV, and that having good biosecurity measures in place can help reduce the spread of the disease.
Anytime animals are co-mingled at events, there is a risk they may be exposed to an infectious disease agent. Some states have cancelled pre-show weigh-ins or other animal commingling events to try to prevent PEDV infection of swine.
Wilkes encourages every person involved in showing livestock to enhance their biosecurity efforts. He noted that the VDACS always urges livestock owners who show their animals, as well as those individuals who manage show and exhibition facilities to keep biosecurity uppermost in their minds.
However, Wilkes said that with swine it is even more important now that Virginia has experienced its first case of PEDV, and that having good biosecurity measures in place can help reduce the spread of the disease.
Anytime animals are co-mingled at events, there is a risk they may be exposed to an infectious disease agent. Some states have cancelled pre-show weigh-ins or other animal commingling events to try to prevent PEDV infection of swine.
Read More here
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